ProtInvTree: Deliberate Protein Inverse Folding with Reward-guided Tree Search

NeurIPSSpotlight2025

Authors
Mengdi Liu, Xiaoxue Cheng, Zhangyang Gao, Hong Chang, Cheng Tan, Shiguang Shan, Xilin Chen
Venue
NeurIPS 2025
Track
Spotlight

TL;DR

Designing protein sequences that fold into a target 3D structure—known as protein inverse folding—is a fundamental challenge in protein engineering…

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Topics

protein 3d

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