Ctrl-DNA: Controllable Cell-Type-Specific Regulatory DNA Design via Constrained RL

NeurIPSSpotlight2025

Authors: Xingyu Chen, Shihao Ma, Runsheng Lin, Jiecong Lin, BO WANG
Venue: NeurIPS 2025
Track: Spotlight

TL;DR

Designing regulatory DNA sequences that achieve precise cell-type-specific gene expression is crucial for advancements in synthetic biology, gene therapy and precision medicine…

Opening excerpt from the authors’ abstract. source

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Topics

biology control

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